Appendix 1. Methodology
For chlormequat analysis, the limit of detection is 10 ppb, and the limit of quantification is 100 ppb. This means we can be certain of chlormequat detections between 10 ppb and 100 ppb. But we can only estimate the concentration.
All products tested were purchased either at grocery stores in the Washington, D.C., metropolitan area or from a major online retailer. Samples were analyzed by Anresco, an independent, accredited laboratory in California, in tests commissioned by EWG.
Appendix 2. EWG health-based limit for chlormequat
EWG develops benchmarks for pesticides to protect children’s health against harms that can be caused by exposure to substances like chlormequat and glyphosate. Our health benchmark for glyphosate is 160 ppb, and for chlormequat it’s 30 ppb.
EWG’s chlormequat benchmark is based on our recommended maximum value for long-term dietary exposures of no more than 0.05 micrograms per kilogram, or µg/kg, body weight per day – 1,000 times smaller and more protective than the EPA’s chronic reference dose of 0.05 mg/kg body weight per day or 50 µg/kg body weight per day.
Our recommendation for the chronic, or daily, daily exposure limit for chlormequat is 0.05 µg/kg body weight per day, calculated as follows:
- Departure point of 5 mg/kg body weight per day, based on the 2020 study by Xiagedeer.
- Application of 10-fold safety factor due to the lack of No Observed Adverse Effect Level
- Application of 10-fold safety factor due to database uncertainty
- Application of 10-fold safety factor due to interspecies differences between animals and humans
- Application of 10-fold safety factor due to sensitivity variation within the human population (intra-species variation)
- Application of a 10-fold safety for children’s health protection.
Based on these calculations, EWG’s health-based limit for daily exposure to chlormequat is 0.05 µg/kg body weight per day.
Translating this concentration to a 60 gram serving of food – a single serving of granola or large bowl of cereal – and the weight of a 6- to 11-year old child (about 30 kilograms) points to a benchmark concentration of no more than 25 nanograms chlormequat per gram of food product, equivalent to 25 ppb.
Similarly, if a child aged 1 to 2 years old weighing about 10 kilograms consumed 15 grams of food, the safe level of chlormequat would be 33 nanograms chlormequat per gram of food, or 33 ppb. So EWG’s health benchmark is 30 ppb for chlormequat in food. This value would also be protective during pregnancy.
"oat" - Google News
January 31, 2023 at 07:00PM
https://ift.tt/N7PvsdC
EWG investigation: Dangerous agricultural chemical chlormequat found in popular oat-based products - Environmental Working Group
"oat" - Google News
https://ift.tt/1tYcIlO
https://ift.tt/3jmEOLp
Bagikan Berita Ini
0 Response to "EWG investigation: Dangerous agricultural chemical chlormequat found in popular oat-based products - Environmental Working Group"
Post a Comment